Inflammation is a response triggered by damage to living tissues.The inflammatory response is a defense mechanism that evolved in higher organisms to protect them from infection and injury.Its purpose is to localize and eliminate the injurious agent and to remove damaged tissue components so that the body can begin to heal. Inflammation is part of the body’s defense mechanism and plays a role in the healing process. The coagulation cascade is activated during tissue injury and during infection.

It is divided into two pathways that converge and ultimately cause the activation of thrombin with the subsequent cleavage of fibrinogen into fibrin . Chronic inflammation refers to a response by your immune system that sticks around long after an infection, injury, or exposure to a toxin.

Inflammation is critical for the development of many complex diseases and disorders including autoimmune diseases, metabolic syndrome, neurodegenerative diseases, cancers, and cardiovascular diseases. What is the Mechanism of Acute Inflammation? ADVERTISEMENTS: The body has the capacity to respond to both minor injuries such as bruising, scratching, cuts, and abrasions, as well as to major injuries such as severe burns and amputation of limbs through inflammation. Interactions of cells in the innate immune system, adaptive immune system, and inflammatory mediators orchestrate aspects of the acute and chronic inflammation that underlie diseases of many organs. Inflammation and coagulation are intimately intertwined. Inflammation (from Latin: inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out necrotic cells and tissues damaged from the original insult and the inflammatory process, and initiate tissue repair. Inflammation comes in two types: chronic inflammation, which can be defined as a dysregulated form of inflammation, and acute inflammation, which can defined as a regulated … The molecular mechanism of inflammation is quite a complicated process which is initiated by the recognition of specific molecular patterns associated with either infection or tissue injury. Inflammation participates importantly in host defenses against infectious agents and injury, but it also contributes to the pathophysiology of many chronic diseases. Article Shared By. When the body detects an intruder, it launches a biological response to try to remove it.